Longitudinal evaluation of dysexecutive vs. amnestic Alzheimer's

 
   Lead Investigator:    Jesse Mez
   Institution      :    Columbia
   E-Mail           :    jbm2154@columbia.edu
   Proposal ID      :    187


   Publications:


1  Mez J, Consentino S, Brickman A, Huey E, Manley J, Mayeux R
   Cognitive and functional decline in dysexecutive versus amnestic Alzheimer's
   Abstract  Alzheimers Dement,8:P635-P636,2012,

   PUBLISHED



2  Mez J, Cosentino S, Brickman AM, Huey ED, Manly JJ, Mayeux R
   Faster cognitive and functional decline in Dysexecutive versus amnestic Alzheimer's subgroups: a longitudinal analysis of the National Alzheimer's Coordinating Center (NACC) database
   Journal Article  PLoS One,8:e65246,2013,PMC3670903

   PUBLISHED



3  Mez J, Cosentino S, Brickman AM, Huey ED, Mayeux R
   Different demographic, genetic, and longitudinal traits in language versus memory Alzheimer's disease subgroups
   Journal Article  J Alzheimers Dis,37:137-146,2013,PMC3877683

   PUBLISHED





   Proposal Description:
   Aims:  1. To compare the baseline and rate of decline of global cognition in  dysexecutive vs amnestic phenotypes in participants with MCI and AD.  2. To compare the baseline and rate of decline of instrumental  activities of daily living in dysexecutive vs. amnestic phenotypes in  participants with MCI and AD.  3. To compare the likelihood of conversion to dementia in dysexecutive  vs. amnestic phenotypes in participant with MCI.